Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development
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منابع مشابه
Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development
The function of Snail2 in mesenchymal tumors is, to date unknown. Using knockdown and overexpression studies, we show that Snail2 regulates migration and invasion of osteosarcoma cells. Knockdown resulted in significantly decreased motility, remodelling of the actin cytoskeleton, and loss of cellular protrusions. Over-expression increased motility, formation of actin-rich cellular protrusions, ...
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2013
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2013.01.027